I've got Actinic Keratosis (AK) in several areas on my body (chest, back of hands, legs, arms). On 2 of the worse spots, I'm using the Perrin's Blend. I think it's been about a week and I'm seeing improvement already on those 2 spots so I've started using it on a 3rd spot. I've been trying everything from products the dermatologist has had me on to alternative remedies I found posted on a skin cancer forum without any luck so this improvement in just a week is great. I'll let you know if I have complete success. I saw your posting on the skin cancer forum. If I have success with this, I'll post my story there.